Package: cvasi Type: Package Title: Calibration, Validation, and Simulation of TKTD Models Version: 1.5.1 Authors@R: c( person("Nils", "Kehrein", email="nils.kehrein@gmail.com", role=c("aut", "cre")), person("Dirk", "Nickisch", role="aut"), person("Peter", "Vermeiren", role="aut"), person("Torben", "Wittwer", role="ctb"), person("Johannes", "Witt", role="ctb"), person("Andre", "Gergs", role="ctb") ) Description: Eases the use of ecotoxicological effect models. Can simulate common toxicokinetic-toxicodynamic (TK/TD) models such as General Unified Threshold models of Survival (GUTS) and Lemna. It can derive effects and effect profiles (EPx) from scenarios. It supports the use of 'tidyr' workflows employing the pipe symbol. Time-consuming tasks can be parallelized. URL: https://github.com/cvasi-tktd/cvasi BugReports: https://github.com/cvasi-tktd/cvasi/issues License: GPL (>= 3) Encoding: UTF-8 LazyData: true Imports: cli, rlang, stringr, dplyr, tibble, purrr, furrr, tidyr, magrittr, utils, stats, methods, grid, gridExtra, ggplot2, GGally, deSolve, lubridate, units, lifecycle RoxygenNote: 7.3.3 Roxygen: list(markdown = TRUE, roclets = c("collate", "namespace", "rd", "roxyglobals::global_roclet")) Config/testthat/edition: 3 Collate: 'batch.R' 'cache.R' 'class-CalibrationSet.R' 'class-ExposureSeries.R' 'class-EffectScenario.R' 'sequence.R' 'calibrate.R' 'class-ParameterSet.R' 'class-Transferable.R' 'data.R' 'dose_response.R' 'effect.R' 'epx.R' 'explore_space.R' 'fx.R' 'solver.R' 'man-lemna.R' 'model-lemna_setac.R' 'model-magma.R' 'model-lemna_schmitt.R' 'fit_growth.R' 'fit_tktd.R' 'get.R' 'get_param.R' 'get_tag.R' 'get_times.R' 'globals.R' 'has.R' 'import_morse.R' 'import_toxswa.R' 'is.R' 'lik_profile.R' 'log.R' 'man-deb.R' 'man-macrophytes.R' 'model-algae.R' 'model-deb_abj.R' 'model-debtox.R' 'model-deb_daphnia.R' 'model-guts.R' 'model-guts_red.R' 'numerics.R' 'package.R' 'pll.R' 'plot.R' 'plotting.r' 'pull.R' 'set.R' 'set_bounds.R' 'set_exposure.R' 'set_forcings.R' 'set_init.R' 'set_param.R' 'set_times.R' 'set_transfer.R' 'set_window.R' 'show.R' 'simulate.R' 'survival.R' 'tox_data.R' 'utils-pipe.R' Suggests: future, knitr, lemna, rmarkdown, roxyglobals, testthat, withr Depends: R (>= 3.5.0) VignetteBuilder: knitr Config/roxyglobals/filename: globals.R Config/roxyglobals/unique: FALSE Config/pak/sysreqs: libicu-dev libssl-dev libudunits2-dev Repository: https://cvasi-tktd.r-universe.dev Date/Publication: 2026-04-10 14:19:34 UTC RemoteUrl: https://github.com/cvasi-tktd/cvasi RemoteRef: HEAD RemoteSha: 4f9cbd39fe98351d15b77a5d34e8b5025bf0d55e NeedsCompilation: yes Packaged: 2026-10-08 08:29:24 UTC; root Author: Nils Kehrein [aut, cre], Dirk Nickisch [aut], Peter Vermeiren [aut], Torben Wittwer [ctb], Johannes Witt [ctb], Andre Gergs [ctb] Maintainer: Nils Kehrein